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Neuer Ansatz für bessere Wirksamkeit von Immuntherapien

Neuer Ansatz für bessere Wirksamkeit von Immuntherapien

The high form of Darmkrebs, the microsatellite-stable colorectal Karzinom (MSS CRC), can now develop a single treatment with modern immunotherapies. A team under the leadership of the medical university can now identify the treatment of the therapeutic therapy and finance a way, a treatment of the patient: this is processed. The study would have been published in the renowned journal „Nature Communications“.

In the Mittelpunkt study of the results of the studies of Victoria Stary (Universitätsklinik für Allgemeinchirurgie, Comprehensive Cancer Center der MedUni Wien and des AKH Wien) there is a special art of immunity, which is thus generated by T-cells, which plays a role in immunotherapy in health care Darmkrebs bisher nicht erforscht wurde. If we have answered the question of the T-cells, the foreign body in the body must first recognize that, if others are suggested by others, the T-cells react directly to your signal, the probability that they will be expanded. The power is one of the most important components of the immune system.

The complex analyses of the Forscher: there is a best group that has cells, which thus generates Vδ1+ T-cells, in the Patient: with MSS CRC the function is not effective, a Krebs is effective in the treatment. As a Solver identification of the Wissenschafter: best Bindegewebszellen (Fibroblasts), the Stoffe Freisetzen, and the Active function of Vδ1+ T-cells blocks. “If we have a refinancing, it is so that this blockade is lifted, as a best molecule TIGIT uses on the Vδ1+ T-cells. So I can not find the T-cells, it was a fact that the Krebs cells were a problem“, reports Victoria Stary from the study.

We have a higher form of Intestinal Krebs
Microsatellite-stable tumors can be with 85 to 90 percent of the colorectal carcinoma aus. I believe that microsatellite-instabile Intestinal Cancer (MSI CRC) patients with MSS CRC have talked about immunotherapies and that the immune system of the immune system is activated by activating tumors. That new won title is a nice way to perform therapies and look at possible options on: “Our research says that it is not the intention that T-cells are used, but that the T-cells play a role in the good form of Intestinal Cancer spielen . Some researchers can get the disease and the disease of others in the tumor environment with a fibroblasts in view, a way to do research in MSS CRC abroad, so Victoria Stary with a click on another research not.