Towards a certain period in the therapy and prevention of diseases

Heidelberger Wissenschaftler beschreiben new Forschungsfeld, een molecularen Grundbausteinen präzise Immunantworten zu gestalten

With the innovative knowledge of synthetic immunology, a new research and methods in the treatment of infectious diseases and credit research are possible, described as a perspective article in the technical manuscript „Nature Nanotechnology“. The Heidelberger scientists Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht and Prof. Dr. Oliver T. Fackler describe a so-called Bottom-up-Verfahren: It is useful for the “toolboxes” of nanotechnology and synthetic biology, a system of molecular masses that are used and that are animated with immunological properties. The experts in synthetic biology, neuroimmunology, parasitology and virology work at the University of Heidelberg, at the Universitätsklinika Heidelberg and Mannheim, at the German Cancer Research Center, which is part of the Max Planck Institute for Medical Research.

With the new bottom-up verification in synthetic immunology, a complex immunological function is not possible by the existing modification of existing or molecular components. If you see the molecular structure of your nano building block or nanotechnology elements, your complex systems will be assembled like this. Basis of technology and engineering of synthetic biology with the design of proteins and peptides, the polymer synthesis or the DNA/RNA modification and the DNA/RNA origami – the three-dimensional ‘failure’ of DNA or RNA strands, a functional nanostructures for erzeugen.

Who the author describes in his summary of the article in „Nature Nanotechnology“, is the new bottom-up analysis in synthetic immunology, a bilingual disinterested treatment and control at the shape of the immune function. Immune components of the Grund-regestellt were, can Immunantworten with greater spezifizität and Effizienz-passgenau be used. Because there is no talk of an end to the treatment in the new therapy and the impfstof, the treatment methods will no longer be effective, but have no effect on a treatment or a treatment.

The bottom-up report of the research into the Heidelberger Wissenschaftler is no longer therapeutic ansätze and methods, which can help to shift the boundaries, was possible with the treatment complexes. If the problem area develops further, it is sensible to develop a composite synthetic immunological immunity. If so, then the vision, the insanity is a vorbeugen and treatment. “We see a certain time in the therapy and prevention of infectious diseases and credits. The synergistic synthetic biology and immunology work together in a disease process, the art and the well-being, how with the illness also, a Tages on a new complete new basis can be put”, according to Prof. Göpfrich.

The Molekularbiologin Kerstin Göpfrich, who was born in the year 2022 and the Ruperto Carola, leads the Research Group “Biophysical Engineering of Life” at the Center for Molekular Biology of the University of Heidelberg (ZMBH); This is the Max Planck Institute for Medical Research. Michael Platten is director of the Neurological Clinic of the Universitätsklinikums Mannheim and director of Mannheimer Zentrums for Translational Neurosciences and of the Medical Facultät Mannheim of the University of Heidelberg, and has been a professor of Neurology innehat since 2016. The Deutschen Krebsforschungszentrum leitet is de Klinische Kooperationseinheit Neuroimmunologie und Hirntumorimmunologie. The parasitologist Friedrich Frischknecht and the virologist Oliver T. Fackler work at the Center for Integrative Infectious Disease Research (CIID), the center for infectious diseases of the Universitätsklinikums in Heidelberg. Prof. Frischknecht has been Professor of Integrative Parasitology since 2014, Prof. Fackler – ebenfalls inhaber Professur an der Medizinischen Fakultät Heidelberg der Universität Heidelberg – published since 2007 in Forschungsbereich Integrative Virologie.